Kayayyaki
Lifecosm CHW Ag/Anaplasma Ab/E.canis Ab Gwajin Kit
Canine Heartworm Ag/Anaplasma Ab /Ehrlichia canis Ab gwajin kit
| Lambar kasida | Saukewa: RC-CF29 |
| Takaitawa | Gano Canine Dirofilaria immitis antigens, Anaplasma antibodies, E. canis antibodies cikin minti 10 |
| Ka'ida | Immunochromatographic mataki-mataki daya |
| Abubuwan Ganewa | CHW Ag: Dirofilaria immitis antigens Anapalsma Ab : Kwayoyin rigakafin AnaplasmaE. canis Ab : E. canis antibodies |
| Misali | Dukan Jini na Canine, Plasma ko Serum |
| Lokacin karatu | Minti 10 |
| Yawan | Akwati 1 (kit) = na'urori 10 (Kit ɗin mutum ɗaya) |
| Abubuwan da ke ciki | Kayan gwaji, kwalaben buffer, da dropper da za a iya zubarwa |
| Adana | Zafin daki (a 2 ~ 30 ℃) |
| Karewa | 24 watanni bayan masana'antu |
| Tsanaki | Yi amfani a cikin minti 10 bayan buɗewaYi amfani da adadin samfurin da ya dace (0.01 ml na dropper) Yi amfani da bayan mintuna 15 ~ 30 a RT idan an adana su a ƙarƙashin yanayin sanyi Yi la'akari da sakamakon gwajin a matsayin mara inganci bayan mintuna 10 |
Bayani
Manya-manyan tsutsotsin zuciya suna girma inci da yawa a tsayi kuma suna zama a cikin arteries na huhu inda za su iya samun isassun abubuwan gina jiki.Ciwon zuciya a cikin arteries yana haifar da kumburi kuma ya haifar da hematoma.Don haka, ya kamata zuciya ta rinka yin busawa fiye da da, yayin da tsutsotsin zuciya ke karuwa da yawa, suna toshe arteries.
Lokacin da kamuwa da cuta ya lalace (sama da tsutsotsin zuciya 25 suna wanzuwa a cikin kare mai nauyin kilogiram 18), tsutsotsin zuciya suna motsawa zuwa cikin atrium na dama, suna toshe kwararar jini.
Lokacin da adadin tsutsotsin zuciya ya kai fiye da 50, za su iya mamayewa
atriums da ventricles.
Lokacin kamuwa da cututtukan zuciya sama da 100 a sashin dama na zuciya, kare ya rasa aikin zuciya kuma a ƙarshe ya mutu.Wannan kisa
Ana kiran sabon abu a matsayin "Caval Syndrom."
Ba kamar sauran ƙwayoyin cuta ba, tsutsotsin zuciya suna kwance ƙananan kwari da ake kira microfilaria.Microfilaria a cikin sauro yana motsawa cikin kare lokacin da sauro ya sha jinin kare.Kwayoyin zuciya da za su iya rayuwa a cikin mai gida na tsawon shekaru 2 suna mutuwa idan ba su koma cikin wani runduna ba a cikin wannan lokacin.Kwayoyin da ke zaune a cikin kare mai ciki na iya harba amfrayonsa.
Binciken farko na tsutsotsin zuciya yana da matukar muhimmanci wajen kawar da su.tsutsotsin zuciya suna bi ta matakai da yawa kamar L1, L2, L3 gami da watsa matakin ta hanyar sauro don zama manyan tsutsotsin zuciya.
Zuciya a cikin sauro
Microfilaria a cikin sauro yana girma zuwa L2 da L3 parasites suna iya cutar da karnuka a cikin makonni da yawa.Girman ya dogara da yanayin.Mafi kyawun zafin jiki don kamuwa da cuta ya wuce 13.9 ℃.
Lokacin da sauro mai kamuwa da cuta ya ciji kare, microfilaria na L3 yana shiga cikin fata.A cikin fata, microfilaria yana girma zuwa L4 don makonni 1 ~ 2.Bayan zama a cikin fata na tsawon watanni 3, L4 yana tasowa zuwa L5, wanda ke motsawa cikin jini.
L5 kamar yadda nau'in ciwon zuciya na manya ya shiga cikin zuciya da jijiyoyin bugun jini inda 5 ~ 7 watanni bayan ciwon zuciya ya kwanta kwari.
Magani
An samu nasarar warkar da kamuwa da cututtukan zuciya a mafi yawan lokuta.Don kawar da duk cututtukan zuciya, amfani da magunguna shine hanya mafi kyau.Gano da wuri na tsutsotsin zuciya yana haɓaka ƙimar nasarar maganin.Duk da haka, a ƙarshen mataki na kamuwa da cuta, rikitarwa na iya faruwa, yana sa maganin ya fi wuya.
Bayani
Kwayar cutar Anaplasma phagocytophilum (tsohon Ehrilichia phagocytophila) na iya haifar da kamuwa da cuta a cikin nau'ikan dabbobi da yawa ciki har da ɗan adam.Cutar da ke cikin naman dabbobin gida kuma ana kiranta da zazzaɓin tick-borne (TBF), kuma an san ta aƙalla shekaru 200.Bacteria na iyali Anaplasmataceae su ne gram-korau, nonmotile, coccoid zuwa kwayoyin ellipsoid, bambanta a girman daga 0.2 zuwa 2.0um diamita.Su ne wajibai aerobes, rashin hanyar glycolytic, kuma dukkansu wajibi ne intracellular parasites.Duk nau'in nau'in halittar Anaplasma suna zaune a cikin ɓangarorin da ke da layin membrane a cikin waɗanda ba su da girma ko balagaggen ƙwayoyin hematopoietic na mammalian mai masaukin baki.Wani phagocytophilum yana cutar da neutrophils kuma kalmar granulocytotropic tana nufin kamuwa da neutrophils.Kwayoyin da ba kasafai ba, an samo su a cikin eosinophils.
Anaplasma phagocytophilum
Alamun
Alamomin asibiti na yau da kullun na anaplasmosis na canine sun haɗa da zazzabi mai zafi, gajiya, damuwa da polyarthritis.Hakanan ana iya ganin alamun neurologic (ataxia, seizures da ciwon wuya).Anaplasma phagocytophilum kamuwa da cuta ba kasafai ake yin kisa ba sai dai in wasu cututtuka masu rikitarwa.An ga hasarar kai tsaye, gurguwar yanayi da asarar samarwa a cikin raguna.An yi rikodin zubar da ciki da raunin maniyyi a cikin tumaki da shanu.Mummunan kamuwa da cuta yana tasiri da abubuwa da yawa, irin su bambance-bambancen na Anaplasma phagocytophilum da ke ciki, sauran ƙwayoyin cuta, shekaru, yanayin rigakafi da yanayin mai gida, da kuma dalilai kamar yanayi da gudanarwa.Ya kamata a ambaci cewa bayyanar asibiti a cikin ɗan adam ya bambanta daga rashin lafiya mai sauƙi mai kama da mura, zuwa kamuwa da cuta mai haɗari.Koyaya, yawancin cututtukan ɗan adam mai yiwuwa suna haifar da ƙarancin bayyanar cututtuka ko rashin bayyanar asibiti.
Watsawa
Anaplasma phagocytophilum ana yada shi ta hanyar ixodid ticks.A {asar Amirka, manyan abubuwan da suka faru sune Ixodes scapularis da Ixodes pacificus, yayin da Ixode ricinus aka gano shi ne babban exophilic vector a Turai.Anaplasma phagocytofilum ana watsa shi ta hanyar waɗannan kaska na vector, kuma babu wata shaida ta watsa transovarial.Yawancin binciken da aka yi a yau wanda ya binciki mahimmancin rundunonin dabbobi masu shayarwa na A. phagocytophilum da kaskansa sun mayar da hankali kan rodents amma wannan kwayar halitta tana da nau'i mai yawa na dabbobi masu shayarwa, yana cutar da kuliyoyi, karnuka, tumaki, shanu, da dawakai.
Bincike
Binciken immunofluorescence kai tsaye shine babban gwajin da ake amfani dashi don gano kamuwa da cuta.Za'a iya ƙididdige samfuran ƙwayar ƙwayar cuta mai ƙarfi da ɗaukar nauyi don neman sauyi sau huɗu a cikin titer antibody zuwa Anaplasma phagocytophilum.Haɗin ciki (morulea) ana iya gani a cikin granulocytes akan smears na jini na Wright ko Gimsa.Ana amfani da hanyoyin sarrafa sarkar polymerase (PCR) don gano Anaplasma phagocytophilum DNA.
Rigakafi
Babu maganin rigakafi da ke samuwa don hana kamuwa da cutar Anaplasma phagocytophilum.Rigakafin ya dogara ne akan guje wa fallasa kaska (Ixodes scapularis, Ixodes pacificus, da Ixode ricinus) daga bazara zuwa kaka, yin amfani da rigakafi na antiacaricides, da yin amfani da doxycycline ko tetracycline lokacin ziyartar Ixodes scapularis, Ixodes pacificus, da Ixodes pacificus. endemic yankuna.
Bayani
Ehrlichia canis karami ne mai siffa mai siffa ta sanda wacce karen kare mai launin ruwan kasa, Rhipicephalus sanguineus ke yadawa.E. canis shine sanadin ehrlichiosis na gargajiya a cikin karnuka.Karnuka na iya kamuwa da cutar ta Ehrlichia spp da yawa.amma mafi yawan abin da ke haifar da canine ehrlichiosis shine E. canis.
E. canis yanzu an san ya bazu ko'ina cikin Amurka, Turai, Kudancin Amurka, Asiya da Bahar Rum.
Karnukan da suka kamu da cutar da ba a kula da su ba za su iya zama masu ɗauke da cutar ta asymptomatic tsawon shekaru kuma a ƙarshe su mutu sakamakon yawan zubar jini.
Alamun
Ehrlichia canis kamuwa da cuta a cikin karnuka ya kasu kashi 3 matakai;
KYAUTA MATSAYI: Wannan gabaɗaya lokaci ne mai laushi.Karen ba zai zama marar lahani ba, ba abinci ba, kuma yana iya zama yana da ƙananan ƙwayoyin lymph.Hakanan ana iya samun zazzabi amma da wuya wannan lokaci ya kashe kare.Yawancin suna share kwayoyin halitta da kansu amma wasu zasu ci gaba zuwa mataki na gaba.
MATSALAR SUBCLINICAL: A cikin wannan lokaci, kare yana bayyana al'ada.Kwayoyin halitta sun rarrabu a cikin magudanar ruwa kuma da gaske suna ɓoye a can.
MATSAYI MAI KYAU: A wannan lokaci kare ya sake yin rashin lafiya.Har zuwa kashi 60 cikin dari na karnuka masu kamuwa da E. canis za su sami zubar jini mara kyau saboda rage adadin platelets.Kumburi mai zurfi a cikin idanu da ake kira "uveitis" na iya faruwa a sakamakon dogon lokaci mai ƙarfafawa na rigakafi.Hakanan ana iya ganin tasirin jijiyoyi.
Bincike da magani
Tabbataccen ganewar asali na Ehrlichia canis yana buƙatar hangen nesa na morula a cikin monocytes akan cytology, gano E. canis serum antibodies tare da gwajin rigakafin rigakafi kai tsaye (IFA), haɓaka sarkar polymerase (PCR), da/ko gel blotting (Western immunoblotting).
Babban tushen rigakafin canine ehrlichiosis shine sarrafa kaska.Maganin zaɓi don magani ga kowane nau'i na ehrlichiosis shine doxycycline na akalla wata ɗaya.Ya kamata a sami ci gaba na asibiti mai ban mamaki a cikin sa'o'i 24-48 bayan fara jiyya a cikin karnuka masu fama da matsananciyar lokaci ko rashin lafiya mai tsanani.A wannan lokacin, adadin platelet ya fara karuwa kuma yakamata ya zama al'ada cikin kwanaki 14 bayan fara magani.
Bayan kamuwa da cuta, yana yiwuwa a sake kamuwa da cutar;rigakafi baya dawwama bayan kamuwa da cuta a baya.
Rigakafi
Mafi kyawun rigakafin ehrlichiosis shine kiyaye karnuka daga kaska.Wannan yakamata ya haɗa da duba fata kowace rana don kaska da kuma kula da karnuka tare da sarrafa kaska.Tun da kaska na ɗauke da wasu cututtuka masu lalacewa, irin su cutar Lyme, anaplasmosis da Dutsen Rocky da aka hange zazzabi, yana da mahimmanci a kiyaye kare kare.
